Peppermint leaf has long been used for both soothing and supporting digestion. A 2013 meta-analysis of randomized, placebo-controlled studies on peppermint oil concluded the therapy to be safe and effective for providing soothing gastrointestinal support. Research indicates that peppermint oil works by acting as a calcium-channel blocker in smooth muscle, thereby relaxing the intestinal smooth muscle.

 

Both fennel and ginger have been used in digestive support for centuries and have a substantial body of data supporting their role in gastrointestinal health. They are both well-known for helping to diminish occasional nausea and for their gastrointestinal soothing effects.