SAMe is a naturally occurring metabolite found in the human body as well as in plant and animal foods. It is the most active of all methyl donors and has been compared to ATP in its importance for the body. SAMe is naturally synthesized in humans from the amino acid methionine in the presence of the cofactors B12 and folate.

SAMe is involved in the synthesis of neurotransmitters‚ the hormone melatonin‚ phospholipids‚ and polyamines‚ which control cellular growth. It is also the source of methyl groups inside the nucleus for DNA methylation‚ which controls gene expression and masking of genetic damage.

These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.

Serving Size: 1 Capsule

Amount Per Serving / % DV

Vitamin B-6 (As Pyridoxal-5-Phosphate) 5mg / 294%
Folate 170mcg DFE / 43%
(As Quatrefolic® [6S]-5-Methyltetrahydrofolate‚ glucosamine salt 200mcg)
Vitamin B-12 (As Methylcobalamin) 50mcg / 2038%
SAMe 200mg / *
(As S-Adenosyl-L-Methionine from SAMe Powder - S-Adenosyl-Methionine P-Tolensulfate‚ Calcium Chloride and Calcium Oxide)

*Daily Value not established.

Other Ingredients: Cellulose (capsule)‚ microcrystalline cellulose‚ vegetable stearate.

Does not contain gluten‚ dairy‚ soy or GMOs.

Manufactured in a GMP Registered Facility in the USA.